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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK4
All Species:
10.91
Human Site:
S412
Identified Species:
21.82
UniProt:
Q96L34
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96L34
NP_113605.2
752
82520
S412
H
S
K
G
Q
R
S
S
S
S
T
Y
H
R
Q
Chimpanzee
Pan troglodytes
XP_512745
736
81102
S397
H
S
K
G
Q
R
S
S
S
S
T
Y
H
R
Q
Rhesus Macaque
Macaca mulatta
XP_001105523
666
73735
K366
F
L
V
L
N
P
A
K
R
C
T
L
E
Q
I
Dog
Lupus familis
XP_541564
690
76525
G389
N
G
T
G
S
S
K
G
T
S
H
S
K
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIP4
752
82625
S412
H
N
K
G
Q
R
A
S
S
S
T
Y
H
R
Q
Rat
Rattus norvegicus
Q8VHF0
797
88733
V409
H
H
K
G
Q
R
S
V
S
S
S
Q
K
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508081
736
82480
S400
P
H
H
K
V
Q
R
S
I
S
S
S
Q
K
Q
Chicken
Gallus gallus
Q9IA88
798
88848
L384
D
S
L
T
S
E
T
L
R
S
S
L
L
Y
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
A442
G
E
E
P
S
P
E
A
M
A
R
Y
L
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
A592
Q
N
D
A
A
A
T
A
A
G
G
T
V
V
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
L212
G
V
I
L
Y
A
L
L
C
G
T
L
P
F
D
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
K333
E
N
E
N
N
D
S
K
K
D
G
S
S
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
75.8
88.4
N.A.
97.6
60.4
N.A.
64.4
32.4
N.A.
29.3
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
100
94.4
77.9
89.3
N.A.
98.9
73.5
N.A.
77.3
50
N.A.
41.2
N.A.
N.A.
N.A.
46.9
N.A.
P-Site Identity:
100
100
6.6
20
N.A.
86.6
53.3
N.A.
20
20
N.A.
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
20
33.3
N.A.
100
73.3
N.A.
40
33.3
N.A.
26.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
17
17
17
9
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
9
0
0
0
9
0
0
0
0
17
% D
% Glu:
9
9
17
0
0
9
9
0
0
0
0
0
9
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
17
9
0
42
0
0
0
9
0
17
17
0
0
9
0
% G
% His:
34
17
9
0
0
0
0
0
0
0
9
0
25
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
9
% I
% Lys:
0
0
34
9
0
0
9
17
9
0
0
0
17
9
0
% K
% Leu:
0
9
9
17
0
0
9
17
0
0
0
25
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
17
% M
% Asn:
9
25
0
9
17
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
9
0
17
0
0
0
0
0
0
9
9
0
% P
% Gln:
9
0
0
0
34
9
0
0
0
0
0
9
9
17
50
% Q
% Arg:
0
0
0
0
0
34
9
0
17
0
9
0
0
25
9
% R
% Ser:
0
25
0
0
25
9
34
34
34
59
25
25
9
9
0
% S
% Thr:
0
0
9
9
0
0
17
0
9
0
42
9
0
0
0
% T
% Val:
0
9
9
0
9
0
0
9
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
34
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _